GENETIC ALGORITHM FOR WARFARIN DOSING

The daily dose of Warfarin, an anti-coagulant, typically takes 5 to 7days, a time period patients suffering from artificial valves, atrialfibration and permilary embolism can ill-afford. In the present study a
genetic algorithm, from the family of evolutionary algorithms, is integrated with artificial neural networks to develop an algorithm to
eliminate the uncertainty of dose and hasten the process of
prescription. The present prescription procedure only takes into account the patients clinical factors. Research shows that genetic factors are 33% responsible of prescription of warfarin dose. The
algorithm stimulates the behavior of a patient taking as input both
clinical and genetic factors of a patient. The algorithm suggests new
values of dose, with each iteration, until the optimum dose is
achieved. The algorithm reduces the one week period of dose
prescription to the matter of seconds.